Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) achieve fame by successfully splicing together the DNA of different animals to create incredible new hybrid animals.

Movie Info Geneticists Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in creating hybrids of species.

The relationship. "[25] Roger Ebert from the Chicago Sun-Times called it "well done and intriguing" but said it is disappointing in that it does not explore Dren's persona.

William Barlow discovers human DNA in Dren's protein samples and arrives to investigate. All the same, it's well done, and intriguing. [4] Guillermo del Toro, Don Murphy, and Joel Silver are the executive producers of this film. Rated R The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes. After Dren exhibits dangerous misbehavior, Elsa restrains Dren and removes her stinger, using it to synthesize the protein that Elsa and Clive had been searching for. There has never been another life form like her. While studying Dren, Elsa and Clive neglect their work with Fred and Ginger. Not so with Dren.

"[9], The film premiered on October 6, 2009 at the Sitges Film Festival,[10] where it won "Best Special Effects" and was in the running for "Best Film", and was part of the 2010 Sundance Film Festival in Park City, Utah. Joan offers Elsa, who is traumatized by her ordeals and now visibly pregnant with Dren's baby, a large sum of money to go through with the pregnancy, which Elsa accepts.

[26] Comparing the film to David Cronenberg's The Brood, Peter Travers from Rolling Stone said, "Played as a child by Abigail Chu and as an adult by Delphine Chanéac, Dren morphs into a special-effects miracle, sexy and scary in equal doses." and William Barlow forbid them from doing this. This creature grows at an astonishing rate, gets smart in a hurry and is soon spelling out words on a Scrabble board without apparently having paused at the intermediate steps of learning to read and write. Disappointing then, that the movie introduces such an extraordinary living being and focuses mostly on those around her. What results is a new form of life, part animal, part human, looking at first like a rounded SpongeBob and then later like a cute kid on Pandora, but shorter and not blue. I wish Dren's persona had been more fully developed. Elsa intervenes and is about to kill Dren, but she hesitates, which allows Dren to kill Clive. (Nucleic Exchange Research and Development).

The centerpiece of the movie is a creature which goes through a dramatic evolutionary process.

Splice is a 2009 science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. Brody and Polley are smart actors, and the director, Vincenzo Natali, is smart, too; do you remember his “The Cube” (1997), with subjects trapped in a nightmarish experimental maze? All of my films end with a question, and somewhat ambiguously, and they always imply the beginning of another story. Clive attacks Dren to save Elsa, but Dren overpowers him. "[24] Lisa Schwarzbaum from Entertainment Weekly gave the film an A− and stated, "The outstanding creature effects by Howard Berger only get more astonishing as Splice splits into an eerie horror picture, then divides again into something out of Rosemary's Baby. Angered, Elsa then mercilessly kills Dren with a rock, before breaking down after Clive was dead. The film, alas, stays resolutely concerned with human problems. Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) achieve fame by successfully splicing together the DNA of different animals to create incredible new hybrid animals. Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use. Click here to see the rest of this review [28] Richard Roeper panned Splice, calling it one of the worst movies of 2010. 19 VIDEOS | 137 IMAGES. (Nucleic Exchange Research & Development), forbids it, instead mandating that their department be reorganized to focus on finding & extracting certain proteins from the creatures they have already created.

Deciding that the only solution is to terminate Dren, they return to the farm and find Dren seemingly already dying. The film was nominated for Best Science Fiction Film at 37th Saturn Awards, but lost to Inception, another film from Warner Bros. Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D. Elsa is later informed that Dren's body contained numerous biochemical compounds for which the company began filing patents.

They lock her in the barn, which seems harsh treatment for the most important achievement of modern biological science. There, Dren displays carnivorous tendencies and retractable wings. Dren has a tail and wings of unspecific animal origin, and hands with three fingers, suggesting a few sloth genes, although Dren is hyperactive. It deals with the divide between hard science and marketable science.

R | 1h 44min | Drama, Horror, Sci-Fi | 4 June 2010 (USA) 1:24 | Trailer. The goal is to create something shocking but also very subtle and completely believable.

After initial success on a small scale, the two plan to splice DNA with a human. What does she feel? Another recent film, “Ricky,” was about the French parents of a child who could fly. They want to push ahead, but the corporation has funded quite enough research for the time being and can't wait to bring the “product” to market. For me—as well as a colleague who saw the film with me—the message here is crystal clear: Don’t play God. The corporation. Elsa says no. Clive thinks they should terminate it. She also evolves more attractive features, based on the Spielberg discovery in “E.T.” that wide-set eyes are attractive. Guillermo del Toro, Don Murphy, and Joel Silverare the executive producers of this film. Dren jumps on him, and he flees, but Elsa notices that Dren has a dangerously high fever. After the presentation, they move Dren to an isolated farm where Elsa grew up. [5] It was aided by Telefilm Canada's funding of US$2.5 million. Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. Splice is a 2009 science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. Clive fully submerges Dren in the sink, intending to kill her, but instead discovers that Dren is amphibious, leaving Elsa in doubt as to his intentions. The movie stays resolutely outside, viewing her as a distant creature.

[17][18] The trailer was attached to two other Warner Bros. movies, The Losers and A Nightmare on Elm Street. Instead, they are to find and extract proteins used for commercial drug production from Fred and Ginger. Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use. [This] is a serious film and an emotional one. [6], In an interview, when asked if there would be any sequels, Natali responded, "I don't think so. [8] Filming took place in Toronto and concluded in February 2008. The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes. Elsa names the creature "Dren" after the creature spells out NERD, having seen the letters on Elsa's shirt.

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